Anti-wrinkle & fillers

Soften lines, restore and define

Collagen stimulators

Gradual firmness and volume

Skin treatments

Texture, tone and radiance

Skin concerns

Acne, scarring and pigmentation

Hair restoration

Thinning, shedding and density

For her & for him

Treatments tailored to you

Not sure which treatment is right for you?

Start with a complimentary consultation. Dr Kris will assess your skin and build a plan around your goals.

Book consultation
Regenerative Skin Treatment

Polynucleotides in Cambridge

A science-led, regenerative treatment for fine lines, dullness, dehydration, under-eye crepiness and loss of firmness, using naturally derived DNA fragments to trigger your skin's own repair processes rather than adding volume.

Doctor-led clinic
12+ years clinical experience
Biologist-led approach
GMC registered
Radiant, healthy skin, polynucleotide treatment result at Kriniko Medical Aesthetics Cambridge
Accredited & recognised by
General Medical Council
British Society of Aesthetics
Joint Council for Cosmetic Practitioners
International Association for Applied Corneotherapy
Dr Kris, Kriniko Medical Aesthetics Cambridge
Led By

Meet Dr Kris: Your Cambridge Polynucleotide Specialist

BSc (Hons) MBBS PgDip MSc RCPathME MRSB MIoL MIHSCM PVRA

Dr Kris combines over 12 years of clinical experience with a professional biologist's understanding of skin regeneration, a rare scientific foundation that shapes every treatment plan at Kriniko Medical Aesthetics.

  • Advanced aesthetic training completed in London, with ongoing continuous professional development in the latest innovative treatments.
  • Deep understanding of how fibroblasts synthesise structural proteins in response to polynucleotides, knowledge grounded in genuine biological training, not trend-following.
  • Every bespoke treatment plan is grounded in published clinical research and rigorous safety protocols.
Is This Right For You?

Concerns Polynucleotides Can Treat

If any of this sounds familiar, polynucleotide therapy could be the regenerative treatment your skin needs.

Fine lines and early wrinkles
Dull, dehydrated skin
Under-eye crepiness and dark circles
Loss of firmness and elasticity
Uneven skin texture
Acne scarring and stretch marks
Thinning hair and scalp health
General signs of skin ageing
Healthy, regenerated skin after polynucleotide treatment at Kriniko Medical Aesthetics
Why Patients Choose This Treatment

The Regenerative Benefits of Polynucleotide Therapy

  • Boosts collagen and elastin productionFor firmer, more structured skin over time.
  • Restores deep hydrationBy binding water molecules within the dermis.
  • Improves elasticity and firmnessReducing skin laxity for a smoother look.
  • Calms inflammation and rednessHelpful for rosacea-prone skin.
  • Delivers natural-looking resultsWorks with your skin's own repair processes, not adding volume.
Why Cambridge Trusts Dr Kris

The Scientific Foundation Behind Every Treatment

12+ years of clinical practice, with both medical and surgical qualifications
  • Treatment tailored to the area being addressed, whether that's the full face, under-eyes, or another targeted concern.
  • Scientific precision: Dr Kris's understanding of facial anatomy ensures polynucleotides are delivered to the exact dermal layer where cellular repair is most effective.
  • Personalised protocols: no two patients receive the same treatment. A thorough skin assessment determines the right approach for your skin type, concerns and goals.
Close-up of healthy, hydrated skin texture
The Kriniko Difference

Science First, Not Trend-Led

Where many practitioners simply deliver injections, Dr Kris understands the molecular mechanisms behind polynucleotide therapy: from how purified DNA fragments stimulate collagen and elastin, to how they help downregulate the pro-inflammatory pathways that accelerate skin ageing.

Scientific precision

Dr Kris's understanding of facial anatomy ensures polynucleotides are delivered to the exact dermal layer where cellular repair is most effective, for natural-looking results.

Personalised protocols

No two patients receive the same treatment. A thorough skin assessment determines the right approach for your skin type, concerns and goals.

Emerging research

Dr Kris stays at the forefront of regenerative aesthetics, incorporating the latest evidence on polynucleotide injectables in aesthetic dermatology.

Our Polynucleotide Services

Find Your Polynucleotide Treatment in Cambridge

Whether you want to improve overall skin quality, tackle under-eye ageing, or treat a targeted area, Dr Kris builds a personalised plan for visible results.

Full face polynucleotide treatment candidate

Full Face Polynucleotide Treatment

Covers the face, neck and décolletage for comprehensive skin rejuvenation, ideal if you're experiencing widespread texture irregularities, loss of elasticity, or early signs of ageing across larger areas.

Polynucleotides act as biocompatible bio-stimulators, encouraging your skin cells to produce more collagen, improve tone, and restore deep hydration from within. Results build gradually over 4 to 12 weeks as regeneration accelerates.

Face, neck & décolletage Collagen stimulation Deep hydration
Under-eye polynucleotide therapy candidate

Under-Eye Polynucleotide Therapy

The delicate under-eye area is often the first to show ageing: thin skin, dark circles and fine lines. Polynucleotides offer a safer alternative to tear trough fillers for patients concerned about this sensitive zone.

As bio-stimulatory agents rather than volumetric fillers, they improve skin thickness and elasticity without the risks associated with filler migration in thin tissue, hydrating and brightening while calming inflammation and redness.

Periocular rejuvenation Brightens & hydrates Filler-free option
Targeted area polynucleotide treatment

Targeted Area Treatment

Beyond the face and under-eyes, polynucleotides deliver powerful results in targeted areas including hands, neck and specific problem zones, including remodelling scars and stretch marks, valuable for acne scarring or post-surgical concerns.

Scalp treatments are also available for hair growth stimulation and follicle health, supporting follicular recovery through boosted collagen and tissue regeneration. Dr Kris tailors each protocol to your specific treatment area and goals.

Hands & neck Scars & stretch marks Scalp & hair follicle health
Your Treatment Journey

What to expect, step by step

Understanding what happens before, during and after your polynucleotide procedure helps set realistic expectations.

01

Consultation & assessment

A thorough skin analysis reviews your history, concerns and goals. From this, Dr Kris builds a bespoke plan covering number of sessions, treatment areas, and expected timeline.

02

The injection treatment

Small injections of highly purified DNA fragments are placed into the targeted skin areas. Topical anaesthetic is used where needed. Treatment takes 30–45 minutes.

03

Follow-up & results

Best results come from 3–4 sessions spaced 2–3 weeks apart. Mild swelling or bumps usually resolve in 24–48 hours, with visible improvement building over the following weeks.

Polynucleotide Treatment Results

Real Results That Build From Within

Results build gradually over 4 to 12 weeks as your skin's own regenerative processes accelerate.

Texture & tone

Smoother, more even complexion with reduced fine lines.

Elasticity & firmness

Measurable improvement, reduced skin laxity.

Deep hydration

Polynucleotides bind water molecules within the dermis.

Collagen production

Long-term improvement in skin structure.

Less inflammation

Calms redness, beneficial for conditions like rosacea.

What does the clinical research show?
Polynucleotides repair damaged and ageing skin at a cellular level: fibroblasts synthesise structural proteins including collagen and elastin in response to treatment, while polynucleotides neutralise free radicals and mitigate oxidative stress. A trial of PN-HPT (High Purification Technology) found meaningful improvements in skin firmness, pigmentation and radiance persisting up to six months, with the majority of patients reporting "Satisfied" or "Very Satisfied" outcomes. Multiple studies demonstrate statistically significant improvements in wrinkle reduction, skin texture and elasticity.
Inside Kriniko

Step Inside Our Cambridge Clinic

A calm, doctor-led clinical space fitted with advanced diagnostic and treatment technology. Take a look inside before you visit.

Doctor-led clinic with advanced skin diagnostic technology at Kriniko Medical Aesthetics Cambridge Doctor-Led Clinic
Modern treatment space at Kriniko Medical Aesthetics Cambridge Modern Space
Private consultation space at Kriniko Medical Aesthetics Cambridge Private Consultation Space

Swipe or scroll to see more →

Frequently Asked Questions

Your Polynucleotide Questions, Answered

How many sessions will I need?
Most patients require two to three sessions, with best outcomes typically seen after 3 to 4 sessions spaced 2 to 3 weeks apart. Results build gradually over 4 to 12 weeks. Maintenance sessions every 6 to 12 months help sustain improvements.
What are the side effects?
Common side effects are mild and temporary: slight swelling, redness or small bumps at injection sites, occasionally minor bruising. These typically resolve within 24 to 48 hours. Across multiple clinical trials, no serious adverse events have been reported with polynucleotide treatments.
Can polynucleotides be combined with other treatments?
Yes. Polynucleotides complement skin boosters like Profhilo, dermal fillers for volumetric correction, and energy-based treatments. Some protocols combine polynucleotides with PRP or microneedling. Dr Kris will advise on the best combination for your goals during consultation.
What's the difference between polynucleotides and dermal fillers?
Dermal fillers restore lost volume by filling hollows and adding structure. Polynucleotides work differently: they stimulate your skin's own repair processes, boosting collagen, improving elasticity, restoring hydration and enhancing skin quality at a cellular level. For significant volume loss, fillers may still be more appropriate, and Dr Kris can advise on the right approach for you.

Book Your Polynucleotide Consultation in Cambridge Today

Your skin deserves treatment grounded in science, not guesswork. Book a comprehensive consultation with Dr Kris and get a bespoke polynucleotide treatment plan built around your goals.

Cambridge Areas We Serve

Polynucleotide Treatment Across Cambridge and Beyond

Central Cambridge Cherry Hinton Trumpington Chesterton Girton Dry Drayton Histon & Impington Bar Hill Cambourne Ely Newmarket St Ives