Regenerative Skin Treatment

Polynucleotides in Cambridge

A science-led, regenerative treatment for fine lines, dullness, dehydration, under-eye crepiness and loss of firmness — using naturally derived DNA fragments to trigger your skin's own repair processes, not add volume.

12+ years clinical experience
Biologist-led approach
GMC registered
Radiant, healthy skin — polynucleotide treatment result at Kriniko Medical Aesthetics Cambridge Kriniko Medical Aesthetics · Cambridge
Accredited & recognised by
General Medical Council British Society of Aesthetics Joint Council for Cosmetic Practitioners International Association for Applied Corneotherapy
Dr Kris, Kriniko Medical Aesthetics Cambridge
Led By

Meet Dr Kris

Dr Kris combines over 12 years of clinical experience with a professional biologist's understanding of skin regeneration — a rare scientific foundation that shapes every treatment plan at Kriniko Medical Aesthetics.

  • Advanced aesthetic training completed in London, with ongoing continuous professional development in the latest innovative treatments.
  • Deep understanding of how fibroblasts synthesise structural proteins in response to polynucleotides — knowledge grounded in genuine biological training, not trend-following.
  • Every bespoke treatment plan is grounded in published clinical research and rigorous safety protocols.

BSc (Hons) MBBS PgDip MSc RCPathME MRSB MIoL MIHSCM PVRA

Why Cambridge Trusts Dr Kris

A rare scientific foundation behind every treatment

12+ years of clinical practice, with both medical and surgical qualifications
  • Treatment tailored to the area being addressed, whether that's the full face, under-eyes, or another targeted concern.
  • Scientific precision — Dr Kris's understanding of facial anatomy ensures polynucleotides are delivered to the exact dermal layer where cellular repair is most effective.
  • Personalised protocols — no two patients receive the same treatment. A thorough skin assessment determines the right approach for your skin type, concerns and goals.
Close-up of healthy, hydrated skin texture
The Kriniko Difference

Science first, trends second

Where many practitioners simply deliver injections, Dr Kris understands the molecular mechanisms behind polynucleotide therapy — from how purified DNA fragments stimulate collagen and elastin, to how they help downregulate the pro-inflammatory pathways that accelerate skin ageing.

Scientific precision

Dr Kris's understanding of facial anatomy ensures polynucleotides are delivered to the exact dermal layer where cellular repair is most effective — for natural-looking results.

Personalised protocols

No two patients receive the same treatment. A thorough skin assessment determines the right approach for your skin type, concerns and goals.

Emerging research

Dr Kris stays at the forefront of regenerative aesthetics, incorporating the latest evidence on polynucleotide injectables in aesthetic dermatology.

Our Polynucleotide Services

Treatment tailored to your skin's needs

Whether you want to improve overall skin quality, tackle under-eye ageing, or treat a targeted area, Dr Kris builds a personalised plan for visible results.

Full face polynucleotide treatment candidate

Full Face Polynucleotide Treatment

Covers the face, neck and décolletage for comprehensive skin rejuvenation — ideal if you're experiencing widespread texture irregularities, loss of elasticity, or early signs of ageing across larger areas.

Polynucleotides act as biocompatible bio-stimulators, encouraging your skin cells to produce more collagen, improve tone, and restore deep hydration from within. Results build gradually over 4–12 weeks as regeneration accelerates.

Face, neck & décolletage Collagen stimulation Deep hydration
Single session£220
Course of three£595
Book This Treatment
Under-eye polynucleotide therapy candidate

Under-Eye Polynucleotide Therapy

The delicate under-eye area is often the first to show ageing — thin skin, dark circles and fine lines. Polynucleotides offer a safer alternative to tear trough fillers for patients concerned about this sensitive zone.

As bio-stimulatory agents rather than volumetric fillers, they improve skin thickness and elasticity without the risks associated with filler migration in thin tissue — hydrating and brightening while calming inflammation and redness.

Periocular rejuvenation Brightens & hydrates Filler-free option
Single session£120
Course of three£320
Book This Treatment
Targeted area polynucleotide treatment

Targeted Area Treatment

Beyond the face and under-eyes, polynucleotides deliver powerful results in targeted areas including hands, neck and specific problem zones — including remodelling scars and stretch marks, valuable for acne scarring or post-surgical concerns.

Scalp treatments are also available for hair growth stimulation and follicle health, supporting follicular recovery through boosted collagen and tissue regeneration. Dr Kris tailors each protocol to your specific treatment area and goals.

Hands & neck Scars & stretch marks Scalp & hair follicle health
From consultationBespoke

Pricing depends on area and number of sessions required.

Discuss Your Goals
Your Treatment Journey

What to expect, step by step

Understanding what happens before, during and after your polynucleotide procedure helps set realistic expectations.

01

Consultation & assessment

A thorough skin analysis reviews your history, concerns and goals. From this, Dr Kris builds a bespoke plan — number of sessions, treatment areas, and expected timeline.

02

The injection treatment

Small injections of highly purified DNA fragments are placed into the targeted skin areas. Topical anaesthetic is used where needed. Treatment takes 30–45 minutes.

03

Follow-up & results

Best results come from 3–4 sessions spaced 2–3 weeks apart. Mild swelling or bumps usually resolve in 24–48 hours, with visible improvement building over the following weeks.

Polynucleotide Treatment Results

Change that builds from within

Results build gradually over 4–12 weeks as your skin's own regenerative processes accelerate.

Texture & tone

Smoother, more even complexion with reduced fine lines.

Elasticity & firmness

Measurable improvement, reduced skin laxity.

Deep hydration

Polynucleotides bind water molecules within the dermis.

Collagen production

Long-term improvement in skin structure.

Less inflammation

Calms redness — beneficial for conditions like rosacea.

What does the clinical research show?
Polynucleotides repair damaged and ageing skin at a cellular level — fibroblasts synthesise structural proteins including collagen and elastin in response to treatment, while polynucleotides neutralise free radicals and mitigate oxidative stress. A trial of PN-HPT (High Purification Technology) found meaningful improvements in skin firmness, pigmentation and radiance persisting up to six months, with the majority of patients reporting "Satisfied" or "Very Satisfied" outcomes. Multiple studies demonstrate statistically significant improvements in wrinkle reduction, skin texture and elasticity.
Cambridge Areas We Serve

Advanced polynucleotide treatment, accessible across the region

Central Cambridge Cherry Hinton Trumpington Chesterton Girton Dry Drayton Histon & Impington Bar Hill Cambourne Ely Newmarket St Ives

Cambridge is a major global hub for nucleic-acid research — from RNA structure and processing to nanoparticle delivery technologies. That research culture is part of why a scientifically-driven approach to polynucleotide therapy fits so naturally here.

More on Cambridge's nucleic-acid research context
Cambridge institutions focus on nucleic-acid research and applications, including RNA structure, processing and regulation, molecular biology, and nucleic-acid chemistry. Researchers study the stabilisation of small regulatory RNAs, RNA diagnostics using nanopore techniques, and abnormal RNA–DNA hybrid structures affecting genome stability. There is significant ongoing work into next-generation polynucleotide medicines and their role in nanomedicine and targeted delivery — although challenges around delivery, size and stability remain an active area of study.
Frequently Asked Questions

Questions, answered

How much do polynucleotide treatments cost in Cambridge?
A single session for full face polynucleotide treatment costs £220, with a course of three available for £595. Under-eye treatment is £120 per session, or £320 for a course of three. Pricing varies by area and number of sessions — Dr Kris will discuss costs transparently at your consultation.
How many sessions will I need?
Most patients require two to three sessions, with best outcomes typically seen after 3–4 sessions spaced 2–3 weeks apart. Results build gradually over 4–12 weeks. Maintenance sessions every 6–12 months help sustain improvements.
What are the side effects?
Common side effects are mild and temporary — slight swelling, redness or small bumps at injection sites, occasionally minor bruising. These typically resolve within 24–48 hours. Across multiple clinical trials, no serious adverse events have been reported with polynucleotide treatments.
Can polynucleotides be combined with other treatments?
Yes. Polynucleotides complement skin boosters like Profhilo, dermal fillers for volumetric correction, and energy-based treatments. Some protocols combine polynucleotides with PRP or microneedling. Dr Kris will advise on the best combination for your goals during consultation.
What's the difference between polynucleotides and dermal fillers?
Dermal fillers restore lost volume — filling hollows and adding structure. Polynucleotides work differently: they stimulate your skin's own repair processes, boosting collagen, improving elasticity, restoring hydration and enhancing skin quality at a cellular level. For significant volume loss, fillers may still be more appropriate — Dr Kris can advise on the right approach for you.

Start your polynucleotide journey in Cambridge

Your skin deserves treatment grounded in science, not guesswork. Book a comprehensive consultation with Dr Kris and get a bespoke polynucleotide treatment plan built around your goals.